ROYESH Stem Cell Biotechnology Institute

Kind of project

Key Partner

Output

Project summary

Research Project in Stem Cells and Regenerative Medicine

Bio-eternity Stem Cell Technology (BEST) Institute

Isolation, purification, Characterization, and Banking of Stem Cell Lineages

SUMMARY

Research Project in Tissue Engineering

Faculty of Food Science and Technology, University of Vigo, Spain

School of Pharmacy, Mashhad University of Medical Sciences

Full-text Article Publication

SUMMARY

Research Project in Stem Cells and Biomaterials

Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences

Full-text Article Publication

SUMMARY

Research Project in Cancer Cells and Tumor Macrophages

Biotechnology Research Center, Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Science

Full-text Article Publication

SUMMARY

Research Project in Stem Cells Differentiation

Royan Institute for Stem Cell Biology and Technology

Royan Institute for Reproductive Biomedicine

Abstract Publication

SUMMARY

Research Project in Stem Cells Homing

Department of Physiology, College of Sciences, Shiraz Branch, Islamic Azad University

Full-text Article Publication

SUMMARY

Research Project in Stem Cells Differentiation

Department of Physiology, College of Sciences, Shiraz Branch, Islamic Azad University

Abstract Article Publication

SUMMARY

Research and Educational Workshops

Department of Stem Cells and Regenerative Biology, Eram Biotechnology Institute, TVTO

Holding Long-term Workshops

SUMMARY

Collaboration in an International Conference

Cardiovascular Research Center, Shiraz University of Medical Sciences

Holding a Stem Cell Workshop

SUMMARY

Collaboration in a National Conference

Academic Center for Education, Culture and Research (ACECR)

Holding a Bioinformatics Workshop

SUMMARY

Summaries

Summaries Of Projects

Research Project in Stem Cells and Regenerative Medicine Summary

Since 2023, the Department of Stem Cells and Regenerative Medicine at ROYESH-SCB Institute has collaborated with BEST Institute to isolate, purify, characterize, and bank some stem cell lineages.

Research Project in Tissue Engineering Summary

This Trilateral research collaboration focuses on a specific natural product, Icariin, and its application to stem cells, cancer, and regenerative medicine, conducted among the Department of Stem Cells and Regenerative Medicine, Department of Cancer and Oncology at ROYESH-SCB Institute, with Applied Biomedical Research Center at Mashhad University of Medical Sciences, and Department of Analytical and Food Chemistry at the University of Vigo, Spain. The research output is an article entitled “Icariin: A Promising Natural Product in Biomedicine and Tissue Engineering”, published in the Journal of Functional Biomaterials (Q1) at MDPI.

Research Project in Stem Cells and Biomaterials Summary

This research collaboration focuses on the key role of biomaterials in cardiovascular stem cell therapy, conducted between the Department of Stem Cells and Regenerative Medicine at ROYESH-SCB Institute, and Medical Toxicology Research Center, School of Medicine at Mashhad University of Medical Sciences. The research output is an article entitled “Stem cell therapy in the heart: Biomaterials as a key route”, published in the Tissue and Cell Journal (Q1) at Elsevier.

Research Project in Cancer Cells and Tumor Macrophages Summary

This research collaboration focuses on inducing balance between M1 and M2 tumor-associated macrophages (TAMs) in favor of benign macrophages (M1), conducted between the Department of Stem Cells and Regenerative Medicine at ROYESH-SCB Institute and Nanotechnology Research Center, School of Pharmacy at Mashhad University of Medical Sciences. The research output is an article entitled “Signal transducer and activator of transcription 3 downregulation in J774A.1 cell line as a model of M2 macrophages in tumor microenvironment”, published in the Journal of Cancer Research and Therapeutics.

Research Project in Stem Cells Differentiation Summary

This research collaboration focuses on the key role of Toll-Like Receptors (TLRs) in stem cell differentiation towards cardiomyocytes (CMs), conducted between the Department of Stem Cells and Regenerative Medicine at ROYESH-SCB Institute and Royan Institute for Stem Cell Biology and Technology. The research output is an abstract entitled “Evaluation of Toll Like Receptors Expression in Cardiomyocyte Differentiation from Human Embryonic Stem Cells”, published in the Cell Journal.

Research Project in Stem Cells Homing Summary

This research collaboration focuses on stem cells homing by activating chemokine receptors in human adipose-derived mesenchymal stem cells primed with a chemical compound, conducted between the Department of Stem Cells and Regenerative Medicine at ROYESH-SCB Institute and the Department of Physiology, College of Sciences at Shiraz Branch Islamic Azad University. The research output is an article entitled “Chemokine receptor’s expression in human adipose-derived mesenchymal stem cells primed with valproic acid”, published in the Comparative Clinical Pathology Journal at Springer.

Research Project in Stem Cells Differentiation Summary

This research collaboration focuses on stem cell differentiation towards insulin-producing cells, conducted between the Department of Stem Cells and Regenerative Medicine at ROYESH-SCB Institute and the Department of Physiology, College of Sciences at Shiraz Branch Islamic Azad University. The research output is an abstract entitled “Differentiation of Human Adipose-Derived Mesenchymal Stem Cells to Insulin-Producing Cells”, published in the Cell Journal.

Research and Educational Workshops Summary

This research and educational collaboration was conducted between the ROYESH-SCB Institute and the Eram Biotechnology Institute to hold Long-Term biotechnology and Stem Cell Workshops based on advanced skill educational standards belonging to TVTO. The output was improving the scientific and research level of students in Biotechnology, Cell and Molecular Biology, and Medicine.

Collaboration in an International Conference Summary

This is a collaboration between ROYESH-SCB Institute and Cardiovascular Research Center at Shiraz University of Medical Sciences to hold a scientific workshop entitled “Isolation, culture and cardiomyocyte differentiation of Rat Bone Marrow Mesenchymal Stem Cells (rBM-MSCs)” during the 3rd International Preventive Cardiology Congress.

Collaboration in a National Conference Summary

This is a collaboration between ROYESH-SCB Institute and the Academic Center for Education, Culture, and Research (ACECR) to hold a Bioinformatics workshop during the 3rd National Agricultural Biotechnology Congress.